For Healthcare Professionals Outside the US
For Healthcare Professionals Outside the US
Adverse reactions |
Any grade n (%) |
Grade 3/4 n (%) |
---|---|---|
Blood and lymphatic system disorders | ||
Anemia | 125 (44.0) | 14 (4.9)* |
Lymphocyte count decreased | 157 (55.3) | 26 (9.2) |
Metabolism and nutrition disorders | ||
Glucose plasma increased | 225 (79.2) | 111 (39.1) |
Decreased appetite | 102 (35.9) | 2 (0.7)* |
Gastrointestinal disorders | ||
Diarrhea | 169 (59.5) | 20 (7.0)* |
Nausea | 133 (46.8) | 8 (2.8)* |
Stomatitisa | 86 (30.3) | 7 (2.5)* |
Vomiting | 81 (28.5) | 2 (0.7)* |
Skin and subcutaneous tissue disorders | ||
Rashb | 147 (51.8) | 55 (19.4)* |
Alopecia | 58 (20.4) | |
General disorders and administration site conditions | ||
Fatiguec | 123 (43.3) | 16 (5.6)* |
Investigations | ||
Weight decreased | 79 (27.8) | 15 (5.3)* |
Blood creatinine increased | 192 (67.6) | 8 (2.8)* |
Gamma-glutamyl transferase increased | 151 (53.2) | 34 (12.0) |
Alanine aminotransferase increased | 125 (44.0) | 12 (4.2)* |
Lipase increased | 121 (42.6) | 20 (7.0) |